JointGlow is the only company built upon low-dose radiotherapy, with a single mission: to cure joint pain.
The Renaissance Institute is one of its premier centers, and we treat more spine and hip low-dose radiotherapy cases than anywhere in the world. This page explains what the treatment is, why it works, and what to expect.
Low-dose radiotherapy — LDRT — uses the same equipment that treats cancer, at a tiny fraction of the dose. A course of radiation for a tumor might total 60 to 70 Gray. A full LDRT course for an arthritic joint totals about 3 to 5, delivered in six to ten brief sessions.
At that dose, radiation is not destroying tissue. It is changing the behavior of the inflammatory cells inside a painful joint — quieting the process that causes swelling, stiffness, and pain.
This is not experimental. European centers, particularly in Germany, have used LDRT for degenerative and inflammatory joint conditions for decades, in hundreds of thousands of patients.
Roughly a fifteenth of a cancer dose, spread across six to ten sessions of about 0.5 Gy each. The bars above are drawn to scale.
Low-dose radiotherapy is widely available in Europe and increasingly offered in the United States. What varies is the dose scheme, the accuracy of delivery, and the judgment of the people planning it. JointGlow was founded to standardize all three.
The physicians and physicists who built JointGlow are the ones publishing the evidence base for LDRT and training other centers in it. This is their primary field, not a service line added alongside cancer work.
Dose, fractionation, and interval are not improvised joint by joint. Each protocol is drawn from the published European experience and refined against our own outcomes, then applied consistently — so what worked for the last patient is what you receive.
Treatment runs on the Varian Edge® with HyperSight™ imaging — the same platform we use for radiosurgery. The joint is imaged and verified in position at every session, so the dose lands where it was planned and nowhere else.
Every plan is designed by a radiation oncologist and a medical physicist and checked before the first session. Nothing is delegated to a template. For spine and hip in particular, that planning experience is what separates a good outcome from a wasted course.
We treat more spine and hip LDRT cases than anywhere in the world. Volume is not a marketing claim here — it is the reason the protocols and the planning are as specific as they are.
In osteoarthritis and tendinopathy, immune cells crowd into the joint lining and release signaling molecules that keep the tissue irritated. The cartilage wear is what shows on imaging, but much of the pain comes from that ongoing inflammatory activity. Low doses of radiation shift it in three ways.
Low-dose radiation makes the blood vessel walls in the joint less sticky, so circulating white blood cells stop adhering and migrating into the tissue. The inflammatory traffic into the joint slows down.
Macrophages — the immune system's cleanup cells — exist in an inflammatory state and a repair state. LDRT pushes the population toward repair, and the joint's chemical environment shifts with it.
The molecules that sensitize nerve endings and drive swelling fall off. Patients usually describe it as the joint becoming quiet rather than numb — the ache recedes, and movement gets easier.
LDRT does not regrow cartilage or reverse structural damage. What it changes is the inflammation and the pain, which for most patients is what limits their day.
A radiation oncologist reviews your imaging and history, confirms LDRT is appropriate for your joint, and answers questions. Nothing is treated this day.
A short imaging session in the treatment position, so the beams can be shaped precisely around your anatomy. About thirty minutes.
Typically twice a week over three to five weeks. You lie on the table, the machine moves around you, and it is over in a few minutes. No needles, no sedation, no recovery time.
Relief usually begins within one to two weeks of finishing and can continue improving for a few months. We check in at six to eight weeks. A second course is possible if needed.
Most people hear "radiation" and think of cancer treatment, and the side effects that come with it. The dose here is different enough that the comparison does not hold. There is no hair loss, no nausea, no fatigue of the kind chemotherapy or high-dose radiation causes.
Most patients report nothing at all during or after treatment. Occasionally there is mild, temporary skin warmth or a brief increase in joint soreness before relief sets in.
The theoretical concern with any radiation is long-term risk. At these doses it is very small, and it decreases with age — which is why LDRT is generally offered to older adults and considered more carefully in younger patients. Your radiation oncologist will discuss where you fall.
LDRT is delivered on standard radiation oncology equipment and billed through standard radiation oncology codes. Coverage still varies by plan and by the joint being treated, so we verify your specific benefits rather than guess.
Before your consultation is scheduled, our team contacts your insurer, confirms your benefits, and determines whether prior authorization is required.
If there is any out-of-pocket cost, you receive a written estimate before treatment begins. No one is surprised by a bill here.
We participate with Medicare and the major commercial plans in Central Florida. Bring your card to the consultation and we handle the rest.
We appeal, with the published evidence attached. If an appeal fails, we tell you plainly and discuss self-pay pricing rather than leaving you to figure it out.
A consultation is a conversation, not a commitment. Most are scheduled within a week. No referral required.
The Renaissance Institute is a proud member of Privia Medical Group. The best doctors in our community have joined together to form Privia Medical Group (PMG), a multi-specialty, high-performance medical group that puts patients first. Our physicians are united by the mission of providing better, more coordinated care for their patients.
To learn more about Privia Medical Group and find other Privia doctors, please visit our website.